Journal of Pediatric Neurology, Pediatric IH Issue
IHRF Scientific Advisor Publishes New IH Research in Journal of Pediatric Neurology's Pediatric IH Issue
September 2015—IHRF Scientific Advisor Conrad Johanson, Ph.D.,whose areas of interest include the choroid plexus (the site in the brain where CSF is produced), and the development of more effective drugs to treat IH, has co-authored new research published in the latest issue of Journal of Pediatric Neurology. This issue also marks the first time an issue of the Journal has been exclusively devoted to pediatric intracranial hypertension research.
One of Dr. Johanson’s studies investigates the role of stimulated sodium transport, increased CSF formation and ICP. According to the study’s abstract, “[e]lucidating the common pathophysiologic transport mechanisms of [IH] in children and adults should help identify novel drugs, with fewer side effects than acetazolamide, to control more finely the CSF formation by choroid plexus.One possible avenue for future treatment of children and adults with IH is to pharmacologically manipulate the sodium and water movements across the choroid plexus secretory tissues that generate ICP.”
The other articles in the Journal address a variety of topics including diagnostic criteria for children, neuroendocrine issues, the role of sex hormones, ultrasound imaging for children, Polycystic Ovarian Syndrome and renal problems. Some of the study abstracts are available at the following links
Molecular Modeling of Cerebrospinal Fluid Dynamics in Pediatric Pseudotumor Cerebri Syndrome: Altered Sodium Transport in Choroid Plexus by Lithium Treatment
Conrad E. Johanson, Vincenzo Salpietro
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555149
Pediatric Pseudotumor Cerebri Syndrome: Recent Insights and Future Directions
Vincenzo Salpietro, Martino Ruggieri, Conrad E. Johanson
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555143
Recent Insights on Pediatric Pseudotumor Cerebri Syndrome Pathophysiology: From the “Unifying Neuroendocrine Perspective” to the “Integrated Bioenergetic–Hormonal Mechanism”
Vincenzo Salpietro, Martino Ruggieri, Daniela Concolino, Conrad E. Johanson, Karl T. Weber
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555146
Clinical Assessment and Differential Diagnosis of Pediatric Pseudotumor Cerebri Syndrome: Pearls and Pitfalls
Christos Fokoloros, Christina Spyridou, Maria Kinali
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555147
Remission of Pseudotumor Cerebri Syndrome after Initiating Pregnancy and Menarche: The Puzzling Role of Female Sex Hormones
Valeria Dipasquale, Anna Claudia Romeo, Rosa Morabito, Dominique De Vivo, Emanuele David, Daniela Impollonia, Giovanni Stroscio, Francesca Granata, Antonio Simone Laganà
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555148
Headache and Diplopia after Rapid Maxillary Expansion: A Clue to Underdiagnosed Pseudotumor Cerebri Syndrome?
Anna Claudia Romeo, Sara Manti, Giuseppe Romeo, Giovanni Stroscio, Valeria Dipasquale, Antonino Costa, Dominique De Vivo, Rosa Morabito, Emanuele David, Salvatore Savasta, Francesca Granata
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555150
Tinnitus and Pediatric Pseudotumor Cerebri Syndrome
Dominique De Vivo, Emanuele David, Anna Claudia Romeo, Antonino Costa, Piero Dotto, Rosa Morabito, Giovanni Stroscio, Enrico Maria Mormina, Francesca Granata, Salvatore Savasta
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555152
Pseudotumor Cerebri Syndrome and Renal Diseases in the Pediatric Population
Roberto Chimenz, Valeria Dipasquale, Dominique De Vivo, Federica Sancetta, Anna Claudia Romeo, Valeria Chirico, Antonio Lacquaniti
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555153
Octreotide: A Therapeutic Option for Pediatric Pseudotumor Cerebri Syndrome?
Paolo Morabito, Salvatore Savasta, Dominique De Vivo, Anna Claudia Romeo, Valeria Dipasquale
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555154
Brain Imaging in Pediatric Pseudotumor Cerebri Syndrome
Emanuele David, Kshitij Mankad
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555155
The Role of Ultrasonography for Assessment of Pseudotumor Cerebri Syndrome in the Emergency Department
Emanuele David, Dario Melita, Pietro Spinelli, Vito Cantisani
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555156
Management of Pediatric Pseudotumor Cerebri Syndrome
Valeria Dipasquale, Gabriella Di Rosa, Salvatore Savasta, Ornella Merlo, Daniela Concolino, Teresa Arrigo
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555157